Research may require the use of hazardous or regulated materials such as chemicals, drugs, infectious microorganisms, human embryonic stem cells, radioactive material, or live animals. Safe and responsible management of these materials by University researchers is essential for securing funding, maintaining a safe environment for personnel, avoiding regulatory penalties, and safeguarding research continuity. Principal Investigators (PIs) are responsible for ensuring that all research materials are managed in a safe and responsible manner. University policy dictates that PIs are accountable for the safety of the laboratory staff, students, researchers, and visitors working under their direction or supervision.